Chronic Kidney Disease (CKD)

What your kidneys actually do every day

Most people think “kidneys make urine.” That’s true — but it’s about a fifth of the job. Here’s the rest of what they’re quietly doing.

Filter waste

Remove toxins and excess nitrogen produced when your body breaks down food and tissues. This is the urine-making job, and it’s the most visible one.

Balance fluid

Hold the right amount of water in your body — not too much, not too little. When kidneys struggle, you may notice swelling in your legs, ankles, or face.

Make red blood cells

Produce a hormone called erythropoietin (EPO) that tells your bone marrow to make red blood cells. When kidneys slow down, EPO drops — which is why CKD often causes tiredness and breathlessness.

Strengthen your bones

Activate vitamin D so your body can absorb calcium and keep bones strong. CKD disrupts this process, which is why your doctor may check your calcium, phosphate, and PTH levels.

Control blood pressure

Make hormones that help regulate your blood pressure. Damaged kidneys cause high BP — and then high BP damages the kidneys further. A circle we want to interrupt.

Keep chemistry in balance

Regulate sodium, potassium, and acid levels in your blood. Subtle imbalances here can affect everything from how your heart beats to how your muscles work.

A clinician reaching towards a projected anatomical illustration of the kidneys, ureters and bladder

When you understand how much your kidneys do, CKD stops sounding like a single problem and starts sounding like what it actually is — a set of jobs that need a little help.

Chapter Two · What you might feel

The body has ways of telling you.

A side-by-side illustration comparing a healthy kidney with a diseased one

Here is something many people find surprising: CKD can be silent for a long time. In the early stages, you may feel completely normal. Your kidneys have enormous reserve capacity — you can lose half of one and still function fine. So most people are not diagnosed because they “felt something” — they’re diagnosed because a routine blood or urine test showed something unexpected.

But as CKD progresses, the body begins to send signals. None of these symptoms, alone, means you have CKD. Each can have many other causes. What matters is the pattern, the persistence, and the combination — especially in people who already have diabetes or high blood pressure.

// Signals to take seriously

Symptoms that may suggest your kidneys need attention

Fatigue and weakness

A tiredness that doesn’t improve with rest — often the first thing people notice.

Swelling in legs, ankles, or face

Especially first thing in the morning — or after a long day on your feet.

Foamy or bubbly urine

Foam that doesn’t go away can mean protein is leaking into urine — a key CKD clue.

Blood in urine

Even faint pinkness deserves a check — this is never something to ignore.

Poor appetite, nausea

A metallic taste, food not tasting right, or feeling full quickly — especially common in later CKD.

Breathlessness

Anaemia from low EPO, or fluid building up — can leave you short of breath climbing stairs or even at rest.

Frequent night urination

Getting up more than once or twice a night — especially new for you — can be a kidney clue.

Itchy skin

Persistent, unexplained itching — especially on the back, arms, or legs — can come from toxins building up.

Difficulty concentrating

A “brain fog” feeling — harder to focus, forgetting things, mind not as sharp as usual.

Muscle cramps

Calf cramps at night, or in the legs during the day — often related to mineral imbalances.

If you have several of these, especially together, talk to your doctor. A simple blood test (for creatinine) and a urine test (for protein) can show within hours whether your kidneys need attention. These tests are inexpensive, painless, and widely available. There is no good reason to wait.

Chapter Three · The five stages

CKD has five stages. Where you are matters.

Doctors describe CKD in five stages, based on a number called eGFR — the estimated glomerular filtration rate. It’s calculated from a blood creatinine test and tells us, roughly, how much filtering work your kidneys can do. A healthy eGFR is around 90 or above. Lower numbers mean less filtering capacity.

Reading what stage you’re at is not a moment for panic. It’s a moment for clarity. Different stages need different things. Early stages are about prevention and slowing-down. Later stages are about preparation and planning. The same person can stay in one stage for many years.

// The Five Stages of CKD · By eGFR

1

// eGFR

≥ 90

Kidneys filter normally — but there is some sign of damage

Protein in urine, blood in urine, or scans showing kidney changes. Most people feel completely well. The job here is to find and treat the underlying cause — often diabetes or blood pressure.

2

// eGFR

60–89

Mild reduction in function

Filtering capacity has dropped a little. Still usually no symptoms. Same goals as Stage 1 — protect what you have, manage diabetes and BP, avoid medications that strain the kidneys.

3

// eGFR

30–59

Moderate reduction in function

This is the stage at which many people are first diagnosed. You may start to notice symptoms — tiredness, mild swelling, changes in urine. A nephrologist’s involvement becomes very important here.

4

// eGFR

15–29

Severe reduction in function

Kidneys are significantly impaired. Symptoms are more likely. Treatment focuses on slowing progression and starting to plan for the possibility of dialysis or transplant — quietly, in good time, without rush.

5

// eGFR

< 15

Kidney failure — also called End Stage Kidney Disease

At this stage, kidneys can no longer keep up with the body’s needs alone. Treatment options become dialysis or transplantation. Many people live full and active lives on both. Your nephrologist will walk you through every option.

A kidney banded into the five stages of chronic kidney disease by eGFR, from normal at 90% or above down to kidney failure below 15%

The crucial thing to understand: being in an early stage does not automatically mean you will reach a later one. Many people stay in Stage 2 or 3 for decades. What you do from this point onwards matters far more than which stage you happen to be in today.

Chapter Four · What CKD is not

Some things you’ve probably heard. Most of them aren’t true.

When people are diagnosed with CKD, friends and relatives mean well — but the information they share is often wrong, or out of date, or applies to a different stage of the disease. Some of the most common things you’ll hear are simply not true.

Here are four of the most common misconceptions, addressed plainly.

Common Misconception

"CKD always leads to dialysis."
"CKD does not always lead to dialysis."

Most people with CKD never need dialysis. Many stay in early stages for decades. Even people in Stage 3 or 4 can stabilise and live the rest of their lives without dialysis. Catching CKD early changes the trajectory enormously.

Common Misconception

"There’s nothing you can do."
"There is plenty that can be done."

There is a great deal you can do. Blood pressure control, blood sugar control, the right diet, the right medications, avoiding the wrong medications, and regular monitoring — these all change the course of CKD substantially.

Common Misconception

"You have to give up everything you enjoy."
"Continue enjoying life to the fullest despite CKD."

Most people with CKD continue to eat, work, travel, and live normally. Some changes are needed — less salt, more attention to certain foods — but the goal is moderation, not deprivation. A good dietitian helps you find what works for your life.

Common Misconception

"Once on dialysis, it’s over."
"Dialysis is not the end, It’s a new beginning."

People on dialysis live full, productive lives — working, traveling, raising families, running businesses. And dialysis is not the only option in late-stage CKD — kidney transplant remains a real possibility, and modern transplant outcomes in India are excellent.

The headline: CKD is a manageable, long-term condition for most people who have it. It is not a death sentence. It is not a guarantee of dialysis. It is a signal that your kidneys need attention — and that attention works.

Chapter Five · What you can do

Six things that make a real difference.

If you take nothing else from this page, take these six things. They are the things that, in clinical practice, repeatedly slow CKD — sometimes dramatically — in people who do them consistently. None of them is dramatic on its own. Their power is in doing them all, every day, for years.

An adult's and a child's cupped hands together holding a paper kidney cut-out

Control your blood pressure

If you have only one number to track, make it this one. High BP damages kidneys; damaged kidneys raise BP. Most nephrologists aim for under 130/80 in CKD — ask yours what your target is and check it at home regularly.

Manage your blood sugar if you have diabetes

Diabetes is the leading cause of CKD in India. Tight blood sugar control protects what’s left of kidney function and slows further damage. Your HbA1c every three months matters more than you think.

Be careful with painkillers

Common over-the-counter painkillers like ibuprofen, diclofenac, and naproxen can damage kidneys with regular use. Paracetamol is safer for most people with CKD. Always ask your nephrologist before taking any new medication — even Ayurvedic or herbal remedies.

Eating for kidneys disease

Less salt. Moderate protein. Plenty of fresh fruit and vegetables (within limits a dietitian will set if needed). Drink enough water but not excessive amounts. Avoid extreme diets — especially high-protein or "detox" plans — without your doctor’s input.

Stay active, but sensibly

Regular moderate exercise — brisk walking, swimming, gentle cycling — helps control BP, blood sugar, and weight. You don’t need to train for a marathon. Thirty minutes a day, most days of the week, is enough to make a measurable difference.

See your nephrologist regularly

A specialist who knows your numbers, watches the trends, and intervenes early when something shifts. Regular check-ins are the single biggest predictor of how well CKD is managed long-term. Don’t skip appointments because you "feel fine."

Chapter Six · When to act quickly

Signs that should not wait.

Most of what we’ve covered so far is about long-term management — things you build into your life over weeks and months. But there are some signs that should prompt you to call your nephrologist or go to a hospital the same day.

Same-day medical attention

Do not wait if you experience any of these

  • Sudden, severe swelling in face, legs, or abdomen
  • Breathlessness at rest or lying down flat
  • Chest pain — especially with breathlessness
  • Sudden drop in urine output over 24 hours
  • Visible blood in urine (pink, red, or cola-coloured)
  • Severe nausea or vomiting preventing you from eating or drinking
  • Confusion, drowsiness, or unusual sleepiness
  • Muscle weakness or palpitations — especially with leg cramps

These can be signs of acute deterioration — sometimes from infection, dehydration, a medication problem, or a fluid imbalance. They are usually treatable when caught quickly. Trust your instinct — if something feels seriously wrong, get checked.

Chapter Seven · Living with CKD

CKD becomes part of life, not the whole of it.

Most of the work of living with CKD is small, daily, repeated. It becomes routine — like brushing your teeth, or wearing a seatbelt. After a few months, the diet, the BP check, the medication schedule simply become how you live. The diagnosis fades from being the centre of your life back to being one part of it.

Work & career

Most people with CKD continue working without interruption. Even with dialysis, many people work full-time — with sessions scheduled around their job. Talk to your employer if you need flexible appointments.

Travel & holidays

You can travel almost anywhere with CKD. Even patients on dialysis travel routinely — AKC and other networks help arrange dialysis sessions in your destination city. Plan ahead; don’t let CKD shrink your world.

Mental wellbeing

A new diagnosis is emotionally heavy. Anxiety and low mood are common — and treatable. Talk to your family, your nephrologist, and if helpful, a counsellor. You don’t have to carry this on your own.

Family & relationships

Bring your family into the conversation. The people who love you want to help — and they help better when they understand. Take a family member to your nephrologist appointments. Share what you’re learning.

Food & eating out

A good kidney diet does not mean eating bland food. You can still eat at restaurants, attend weddings, celebrate festivals. A dietitian will help you find ways to enjoy food while protecting your kidneys.

Routine & follow-up

Lab tests every few months. A nephrologist appointment every 3–6 months. Medication adjustments as needed. This rhythm becomes part of your life — and it is what keeps CKD stable.

You’re Not Alone in This

One in seven adults in India lives with some stage of chronic kidney disease. What you learn over the coming months, the changes you make to your daily life, and the partnership you build with your nephrologist are what will determine how this story goes. And for most people who do this work consistently — the story goes well.

We are here to help :
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